Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective.

  title={Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective.},
  author={Sam Virtue and Antonio Vidal-Puig},
  journal={Biochimica et biophysica acta},
  volume={1801 3},
While the link between obesity and type 2 diabetes is clear on an epidemiological level, the underlying mechanism linking these two common disorders is not as clearly understood. One hypothesis linking obesity to type 2 diabetes is the adipose tissue expandability hypothesis. The adipose tissue expandability hypothesis states that a failure in the capacity for adipose tissue expansion, rather than obesity per se is the key factor linking positive energy balance and type 2 diabetes. All… CONTINUE READING
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Adipose tissue expandability , lipotoxicity and the Metabolic Syndrome - - an allostatic perspective

S Virtue, A Vidal-Puig
Biochim Biophys Acta • 2010

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