Adipose tissue engineering based on mesenchymal stem cells and basic fibroblast growth factor in vitro.

@article{Neubauer2005AdiposeTE,
  title={Adipose tissue engineering based on mesenchymal stem cells and basic fibroblast growth factor in vitro.},
  author={Markus Neubauer and Michael C Hacker and Petra Bauer-Kreisel and Barbara Weiser and Claudia Fischbach and Michaela B Schulz and Achim M Goepferich and Torsten Blunk},
  journal={Tissue engineering},
  year={2005},
  volume={11 11-12},
  pages={1840-51}
}
Despite the clinical need for reconstructive and plastic surgery, the supply of engineered adipose tissue equivalents still remains a challenge. As yet, only preadipocytes have been applied as a cell material for the in vitro tissue engineering of fat. Herein, we report the establishment of a three-dimensional (3-D) long-term cell culture, using bone marrow-derived mesenchymal stem cells (MSCs) as an alternative cell source and custom-made poly(lactic-co-glycolic acid) (PLGA) scaffolds as a… CONTINUE READING