Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome.

@article{Spritzer2015AdiposeTD,
  title={Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome.},
  author={Poli Mara Spritzer and Sheila Bunecker Lecke and Fab{\'i}ola Satler and D{\'e}bora Martinho Morsch},
  journal={Reproduction},
  year={2015},
  volume={149 5},
  pages={R219-27}
}
Polycystic ovary syndrome (PCOS), a complex condition that affects women of reproductive age, is characterized by ovulatory dysfunction and androgen excess. Women with PCOS present higher prevalence of obesity, central adiposity, and dyslipidemia, and face increased risk of type 2 diabetes. PCOS is closely linked to functional derangements in adipose tissue. Adipocytes seem to be prone to hypertrophy when exposed to androgen excess, as experienced by women with PCOS, and both adipose tissue… CONTINUE READING

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