Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats.

@article{Corporeau2006AdiposeTC,
  title={Adipose tissue compensates for defect of phosphatidylinositol 3'-kinase induced in liver and muscle by dietary fish oil in fed rats.},
  author={Charlotte Corporeau and Christelle Le Foll and Mohammed Taouis and J. P. Gouygou and J. P. Berge and Jacques Delarue},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={2006},
  volume={290 1},
  pages={E78-E86}
}
The present work aimed to study in rats whether substitution of a low level of fish oil (FO; 2.2% of calories) into a low-fat diet (6.6% of calories from fat as peanut-rape oil or control diet) 1) has a tissue-specific effect on insulin signaling pathway and 2) prevents dexamethasone-induced alteration of insulin signaling in liver, muscle, and adipose tissue. Sixteen rats were used for study of insulin signaling, and sixteen rats received an oral glucose load (3 g/kg). Eight rats/group… CONTINUE READING

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