Adipose tissue browning and metabolic health

  title={Adipose tissue browning and metabolic health},
  author={Alexander Bartelt and Joerg Heeren},
  journal={Nature Reviews Endocrinology},
Accumulation of excess white adipose tissue (WAT) has deleterious consequences for metabolic health. The activation of brown adipose tissue (BAT), the primary organ for heat production, confers beneficial effects on adiposity, insulin resistance and hyperlipidaemia, at least in mice. As the amount of metabolically active BAT seems to be particularly low in patients with obesity or diabetes mellitus who require immediate therapy, new avenues are needed to increase the capacity for adaptive… CONTINUE READING