Adipose tissue as an immunological organ: Toll-like receptors, C1q/TNFs and CTRPs.

@article{Schaeffler2007AdiposeTA,
  title={Adipose tissue as an immunological organ: Toll-like receptors, C1q/TNFs and CTRPs.},
  author={Andreas Schaeffler and Juergen Schoelmerich and Bernd Salzberger},
  journal={Trends in immunology},
  year={2007},
  volume={28 9},
  pages={393-9}
}
Adipose tissue has long been regarded as a mostly resting tissue that is dedicated solely to energy storage and release. However, in recent years, this view has changed dramatically following new insights into the metabolic and immunological functions of preadipocytes and adipocytes. There are several lines of evidence for the involvement of adipose tissue in innate and acquired immune responses. First, adipocytes are potent producers of proinflammatory cytokines, such as interleukin-6 and… CONTINUE READING