Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.

@article{Wang2012AdiposeTA,
  title={Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.},
  author={Yuan-Yuan Wang and Camille Lehu{\'e}d{\'e} and Victor Laurent and B{\'e}atrice Dirat and St{\'e}phanie Dauvillier and Ludivine Bochet and Sophie Le Gonidec and Ghislaine Escourrou and Philippe Valet and Catherine Muller},
  journal={Cancer letters},
  year={2012},
  volume={324 2},
  pages={142-51}
}
Among the many different cell types surrounding breast cancer cells, the most abundant are those that compose mammary adipose tissue, mainly mature adipocytes and progenitors. New accumulating recent evidences bring the tumor-surrounding adipose tissue into the light as a key component of breast cancer progression. The purpose of this review is to emphasize the role that adipose tissue might play by locally affecting breast cancer cell behavior and subsequent clinical consequences arising from… CONTINUE READING