Adipose stem cells can secrete angiogenic factors that inhibit hyaline cartilage regeneration

@inproceedings{Lee2012AdiposeSC,
  title={Adipose stem cells can secrete angiogenic factors that inhibit hyaline cartilage regeneration},
  author={Christopher S. D. Lee and Olivia A. Burnsed and Vineeth Raghuram and Jonathan F. Kalisvaart and Barbara D Boyan and Zvi Schwartz},
  booktitle={Stem Cell Research & Therapy},
  year={2012}
}
Adipose stem cells (ASCs) secrete many trophic factors that can stimulate tissue repair, including angiogenic factors, but little is known about how ASCs and their secreted factors influence cartilage regeneration. Therefore, the aim of this study was to determine the effects ASC-secreted factors have in repairing chondral defects. ASCs isolated from male Sprague Dawley rats were cultured in monolayer or alginate microbeads supplemented with growth (GM) or chondrogenic medium (CM). Subsequent… CONTINUE READING
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