Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis.

@article{Maumus2013AdiposeMS,
  title={Adipose mesenchymal stem cells protect chondrocytes from degeneration associated with osteoarthritis.},
  author={Marie Maumus and Cristina Manferdini and Karine Toupet and Julie-Anne Peyrafitte and Rosanna Ferreira and Andrea Facchini and Elena Gabusi and Philippe Bourin and Christian Jorgensen and Gina Lisignoli and Dani{\'e}le No{\"e}l},
  journal={Stem cell research},
  year={2013},
  volume={11 2},
  pages={834-44}
}
Our work aimed at evaluating the role of adipose stem cells (ASC) on chondrocytes from osteoarthritic (OA) patients and identifying the mediators involved. We used primary chondrocytes, ASCs from different sources and bone marrow mesenchymal stromal cells (MSC) from OA donors. ASCs or MSCs were co-cultured with chondrocytes in a minimal medium and using… CONTINUE READING