Adipose-derived stem cells retain their regenerative potential after methotrexate treatment.

Abstract

In musculoskeletal tissues like bone, chemotherapy can impair progenitor cell differentiation and proliferation, resulting in decreased bone growth and mineralization throughout a patient׳s lifetime. In the current study, we investigated the effects of chemotherapeutics on adipose-derived stem cell (ASC) function to determine whether this cell source could… (More)
DOI: 10.1016/j.yexcr.2014.06.015

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