Adipose-derived stem cells reduce liver oxidative stress and autophagy induced by ischemia-reperfusion and hepatectomy injury in swine.

@article{Ge2018AdiposederivedSC,
  title={Adipose-derived stem cells reduce liver oxidative stress and autophagy induced by ischemia-reperfusion and hepatectomy injury in swine.},
  author={Yansong Ge and Qianzhen Zhang and Zhihui Jiao and Hui Li and Ge Bai and Hongbin Wang},
  journal={Life sciences},
  year={2018},
  volume={214},
  pages={
          62-69
        }
}
AIMS Hepatic ischemia-reperfusion (I/R) injury is an unavoidable complication of liver surgery, often resulting in postoperative complications and liver dysfunction. Adipose-derived stem cells (ADSCs) have been recognized as a potential tool to be exploited in the field of regenerative medicine for the treatment of a variety of diseases. In the present study, the efficacy of ADSCs in a porcine I/R model of laparoscopic hepatectomy was evaluated. MAIN METHODS Twelve Bama miniature pigs were… CONTINUE READING

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