Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.

@article{Wang2004AdiponectinR1,
  title={Adiponectin receptor 1 gene (ADIPOR1) as a candidate for type 2 diabetes and insulin resistance.},
  author={Hua Wang and Hailing Zhang and Yiwen Jia and Zhengxian Zhang and Rebekah L. Craig and Xiao-Qin Wang and S. C. Elbein},
  journal={Diabetes},
  year={2004},
  volume={53 8},
  pages={
          2132-6
        }
}
Considerable data support adiponectin as an important adipose-derived insulin sensitizer that enhances fatty acid oxidation and alters hepatic gluconeogenesis. Adiponectin acts by way of two receptors, ADIPOR1 and ADIPOR2. ADIPOR1 is widely expressed in tissues, including muscle, liver, and pancreas, and binds the globular form of adiponectin with high affinity. To test the hypothesis that sequence variations in or near the ADIPOR1 gene contribute to the risk of developing type 2 diabetes and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 49 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

Similar Papers

Loading similar papers…