Adiponectin multimeric complexes and the metabolic syndrome trait cluster.

  title={Adiponectin multimeric complexes and the metabolic syndrome trait cluster.},
  author={Cristina Lara-Castro and Nanlan Luo and Penny Wallace and Richard L. Klein and W Timothy Garvey},
  volume={55 1},
Adiponectin circulates in human plasma mainly as a 180-kDa low molecular weight (LMW) hexamer and a high molecular weight (HMW) multimer of approximately 360 kDa. We comprehensively examined the relationships between circulating levels of total adiponectin, adiponectin multimers, and the relative distribution (i.e., ratio) of multimeric forms with key features of the metabolic syndrome. Total adiponectin (r = 0.45), HMW (r = 0.47), LMW (r = 0.31), and HMW-to-total adiponectin ratio (r = 0.29… CONTINUE READING


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