Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.

@article{Yamaguchi2007AdiponectinIO,
  title={Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans.},
  author={Noboru Yamaguchi and Toshio Kukita and Yin-ji Li and Jose Guillermo Martinez Argueta and Toshiyuki Saito and Shigemasa Hanazawa and Yoshihisa Yamashita},
  journal={FEMS immunology and medical microbiology},
  year={2007},
  volume={49 1},
  pages={28-34}
}
Previous epidemiologic studies have suggested that periodontal disease is closely related to obesity and glucose tolerance. As the level of adiponectin, an adipocyte-derived cytokine, in plasma had been reported to decrease in obese and type 2 diabetes patients, we explored the role of adiponectin in the etiology of periodontitis using the D clone of RAW264, a clone that exhibits highly efficient osteoclast formation, to determine whether adiponectin acts as a regulatory molecule in osteoclast… CONTINUE READING

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As the level of adiponectin , an adipocyte - derived cytokine , in plasma had been reported to decrease in obese and type 2 diabetes patients , we explored the role of adiponectin in the etiology of periodontitis using the D clone of RAW264 , a clone that exhibits highly efficient osteoclast formation , to determine whether adiponectin acts as a regulatory molecule in osteoclast formation stimulated by lipopolysaccharide of periodontopathic bacteria .
As the level of adiponectin , an adipocyte - derived cytokine , in plasma had been reported to decrease in obese and type 2 diabetes patients , we explored the role of adiponectin in the etiology of periodontitis using the D clone of RAW264 , a clone that exhibits highly efficient osteoclast formation , to determine whether adiponectin acts as a regulatory molecule in osteoclast formation stimulated by lipopolysaccharide of periodontopathic bacteria .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
TRANSCRIPTION FACTORIs biochemical function of gene productNF-kappa B
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
Because NF - kappaB is an important transcription factor in osteoclast formation , we examined the effect of adiponectin on its transcriptional activity .
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