Adiponectin induces interleukin-6 production and activates STAT3 in adult mouse cardiac fibroblasts.

@article{Liao2009AdiponectinII,
  title={Adiponectin induces interleukin-6 production and activates STAT3 in adult mouse cardiac fibroblasts.},
  author={Wenqiang Liao and Changan Yu and Jianyan Wen and William WeiGuo Jia and Geng Li and Yuannan Ke and Shumin Zhao and William B. Campell},
  journal={Biology of the cell},
  year={2009},
  volume={101 5},
  pages={263-72}
}
BACKGROUND INFORMATION APN (adiponectin), an adipocyte-derived cytokine highly presented in serum, which exerts antidiabetic, anti-atherosclerotic and cardioprotective actions, also enhances CFB (cardiac fibroblast) proliferation and protects against cardiac fibrosis. STAT3 (signal transducer and activator of transcription 3), a major mediator in the gp130/JAK2 (Janus kinase 2)/STATs signalling pathway, plays a critical role in cardioprotective events. Almost two-thirds of total myocardial… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…