Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure.

@article{Sam2010AdiponectinDD,
  title={Adiponectin deficiency, diastolic dysfunction, and diastolic heart failure.},
  author={Flora Sam and Toni-Ann S. Duhaney and Kaori Sato and Richard M. Wilson and Koji Ohashi and Saki Sono-Romanelli and Akiko Higuchi and Deepa S de Silva and Fuzhong Qin and Kenneth Walsh and Noriyuki Ouchi},
  journal={Endocrinology},
  year={2010},
  volume={151 1},
  pages={322-31}
}
Aldosterone infusion results in left ventricular hypertrophy (LVH) and hypertension and may involve profibrotic and proinflammatory mechanisms. In turn, hypertension is the major cause of diastolic heart failure (HF). Adiponectin, an adipose-derived plasma protein, exerts antiinflammatory and anti-hypertrophic effects and is implicated in the development of hypertension and systolic HF. We thus tested the hypothesis that hypoadiponectinemia in aldosterone-induced hypertension exacerbated… CONTINUE READING

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Adiponectin and Diastolic Heart Failure Endocrinology

  • V Robert, S Besse, +4 authors Sam
  • For personal use only. No other uses without…
  • 2010
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