Adiponectin as an anti-inflammatory factor.

  title={Adiponectin as an anti-inflammatory factor.},
  author={Noriyuki Ouchi and Kenneth Walsh},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  volume={380 1-2},
Obesity is characterized by low-grade systemic inflammation. Adiponectin is an adipose tissue-derived hormone, which is downregulated in obesity. Adiponectin displays protective actions on the development of various obesity-linked diseases. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways… CONTINUE READING
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