Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human.

@article{Richards2012AdiponectinAI,
  title={Adiponectin and its receptors modulate granulosa cell and cumulus cell functions, fertility, and early embryo development in the mouse and human.},
  author={Joanne S. Richards and Zhilin Liu and Tomoko Kawai and Kei Tabata and Hirohiko Watanabe and Deepa Suresh and Fang-Ting Kuo and Margareta D Pisarska and Masayuki Shimada},
  journal={Fertility and sterility},
  year={2012},
  volume={98 2},
  pages={
          471-9.e1
        }
}
OBJECTIVE To study the expression and function of adiponectin and its receptors in mouse and human follicle cells and in early embryo development. DESIGN Whole ovaries, granulosa cells, and cumulus-oocyte complexes isolated from immature mice before and during hormone-induced ovulation were used to analyze the expression of adiponectin, its receptors, and ovulation-related genes; human cumulus cells and granulosa cells were isolated from patients undergoing in vitro fertilization (IVF… CONTINUE READING

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