Adiponectin Pretreatment Counteracts the Detrimental Effect of a Diabetic Environment on Endothelial Progenitors

@inproceedings{Leicht2011AdiponectinPC,
  title={Adiponectin Pretreatment Counteracts the Detrimental Effect of a Diabetic Environment on Endothelial Progenitors},
  author={Simon F. Leicht and Theresa Maria Schwarz and Patrick C. Hermann and J{\"u}rgen Seissler and Alexandra Aicher and Christopher Heeschen},
  booktitle={Diabetes},
  year={2011}
}
OBJECTIVE It has been shown that vascular progenitors from patients with diabetes are dysfunctional. However, therapeutic strategies to counteract their reduced functional capacity are still lacking. Because adiponectin has reported salutary effects on endothelial function, we investigated the functional effects of globular adiponectin (gAcrp), the active domain of adiponectin, on isolated endothelial colony-forming cells (ECFC). RESEARCH DESIGN AND METHODS ECFC were isolated from peripheral… CONTINUE READING

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