Adiponectin G276T gene polymorphism is associated with cardiovascular disease in Japanese patients with type 2 diabetes.

@article{Katakami2012AdiponectinGG,
  title={Adiponectin G276T gene polymorphism is associated with cardiovascular disease in Japanese patients with type 2 diabetes.},
  author={Naoto Katakami and Hideaki Kaneto and Taka-aki Matsuoka and Mitsuyoshi Takahara and Norikazu Wako Maeda and Ikki Shimizu and Keizo Ohno and Takeshi Osonoi and Koichi Kawai and Fukashi Ishibashi and Kenichi Imamura and Atsunori Kashiwagi and Ryuzo Kawamori and Munehide Matsuhisa and Tohru Funahashi and Yoshimitsu Yamasaki and Iichirou Shimomura},
  journal={Atherosclerosis},
  year={2012},
  volume={220 2},
  pages={
          437-42
        }
}
OBJECTIVE Adiponectin has anti-atherogenic properties and reduced serum adiponectin levels are associated with cardiovascular disease (CVD). In this study, we examined the relationship between CVD and adiponectin (ADIPOQ) gene G276T polymorphism that is associated with serum adiponectin level in a large cohort of type 2 diabetic patients. RESEARCH DESIGN AND METHODS We enrolled 2637 Japanese type 2 diabetic subjects (males, 61.1%; age, 54.9±7.9 years old), determined their genotypes regarding… CONTINUE READING
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