Adiponectin: mechanistic insights and clinical implications

@article{Turer2012AdiponectinMI,
  title={Adiponectin: mechanistic insights and clinical implications},
  author={Aslan T. Turer and Phillip E Scherer},
  journal={Diabetologia},
  year={2012},
  volume={55},
  pages={2319-2326}
}
Adiponectin is an adipocyte-derived secretory protein that has been very widely studied over the past 15 years. A multitude of different functions have been attributed to this adipokine. It has been characterised in vitro at the level of tissue culture systems and in vivo through genetic manipulation of rodent models. It is also widely accepted as a biomarker in clinical studies. Originating in adipose tissue, generally positive metabolic effects have been attributed to adiponectin. In this… CONTINUE READING
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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin

  • WL Holland, RA Miller, ZV Wang
  • Nat Med
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