Adiponectin/T-cadherin and apelin/APJ expression in human arteries and periadventitial fat: implication of local adipokine signaling in atherosclerosis?

@article{Kostopoulos2014AdiponectinTcadherinAA,
  title={Adiponectin/T-cadherin and apelin/APJ expression in human arteries and periadventitial fat: implication of local adipokine signaling in atherosclerosis?},
  author={Christos G Kostopoulos and Sofia G Spiroglou and John N. Varakis and Efstratios E Apostolakis and Helen Papadaki},
  journal={Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology},
  year={2014},
  volume={23 3},
  pages={131-8}
}
INTRODUCTION Adipose tissue is considered an endocrine organ, producing bioactive peptides, called adipokines. Adipokines produced by periadventitial fat have been implicated in the pathogenesis of vascular disease, including atherosclerosis. Adiponectin has established antiatherogenic actions, while the role of T-cadherin as an adiponectin receptor is not fully elucidated. The apelinergic system, consisting of apelin and its APJ receptor, is a mediator of various cardiovascular functions and… CONTINUE READING

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