Adiponectin, interleukin-6, monocyte chemoattractant protein-1, and regional fat mass during 12-month randomized treatment with metformin and/or oral contraceptives in polycystic ovary syndrome.

@article{Glintborg2014AdiponectinIM,
  title={Adiponectin, interleukin-6, monocyte chemoattractant protein-1, and regional fat mass during 12-month randomized treatment with metformin and/or oral contraceptives in polycystic ovary syndrome.},
  author={Dorte Glintborg and Hanne Mumm and Magda Lambaa Altinok and Bj\orn Richelsen and Jens Meldgaard Bruun and Marianne Andersen},
  journal={Journal of endocrinological investigation},
  year={2014},
  volume={37 8},
  pages={757-764}
}
CONTEXT Central obesity in polycystic ovary syndrome (PCOS) is associated with increased inflammatory markers and increased risk for type 2 diabetes. OBJECTIVE To evaluate if improved body composition during treatment with metformin (M) vs. oral contraceptive pills (OCP) was associated with changes in circulating adiponectin, interleukin (IL)-6, and monocyte chemoattractant protein (MCP)-1. PATIENTS AND INTERVENTIONS Ninety patients with PCOS were randomized to 12-month treatment with M (2… CONTINUE READING
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