Adiponectin, diabetes, and coronary heart disease in older persons: unraveling the paradox.

@article{Sattar2008AdiponectinDA,
  title={Adiponectin, diabetes, and coronary heart disease in older persons: unraveling the paradox.},
  author={Naveed 4 Sattar and Scott B. Maresh Nelson},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 9},
  pages={3299-301}
}
Adiponectin is the most abundant circulating peptide hormone secreted by adipocytes and operates in conjunction with its two membrane receptors ADIPOR1 and ADIPOR2 in multiple systems to induce improvement of skeletal muscle and hepatic sensitivity to insulin. More recently T-cadherin has recently been recognized as a novel adiponectin receptor on vascular endothelial cells and smooth muscle. However, despite being secreted by adipocytes, circulating levels of adiponectin decline with obesity… CONTINUE READING
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