Adipokinetic hormones and their G protein-coupled receptors emerged in Lophotrochozoa

@inproceedings{Li2016AdipokineticHA,
  title={Adipokinetic hormones and their G protein-coupled receptors emerged in Lophotrochozoa},
  author={Shizhong Li and Frank Hauser and Signe K. Skadborg and Stine V. Nielsen and Nikolaj Kirketerp-M\oller and Cornelis J. P. Grimmelikhuijzen},
  booktitle={Scientific reports},
  year={2016}
}
Most multicellular animals belong to two evolutionary lineages, the Proto- and Deuterostomia, which diverged 640-760 million years (MYR) ago. Neuropeptide signaling is abundant in animals belonging to both lineages, but it is often unclear whether there exist evolutionary relationships between the neuropeptide systems used by proto- or deuterostomes. An exception, however, are members of the gonadotropin-releasing hormone (GnRH) receptor superfamily, which occur in both evolutionary lineages… CONTINUE READING