Adipokines--targeting a root cause of cardiometabolic risk.

  title={Adipokines--targeting a root cause of cardiometabolic risk.},
  author={Ameet Bakhai},
  journal={QJM : monthly journal of the Association of Physicians},
  volume={101 10},
Obesity often co-presents with other cardiometabolic risk factors such as dyslipidaemia, insulin resistance and hypertension. Less well appreciated is that dysregulation of adipokine production by excess adipose tissue also promotes a state of low-level systemic chronic inflammation and a prothrombotic state, implicated in the development of both atherosclerosis and subsequently cardiovascular events. Lifestyle modification and pharmacological therapy can reduce cardiometabolic risk, a benefit… CONTINUE READING

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