Adipokine protein expression pattern in growth hormone deficiency predisposes to the increased fat cell size and the whole body metabolic derangements.

@article{Ukropec2008AdipokinePE,
  title={Adipokine protein expression pattern in growth hormone deficiency predisposes to the increased fat cell size and the whole body metabolic derangements.},
  author={Jozef Ukropec and Adela Penesov{\'a} and Martina {\vS}kopkov{\'a} and Mikul{\'a}{\vs} Pura and Miroslav Vlcek and Žofia R{\'a}dikov{\'a} and Richard Imrich and Barbara Ukropcov{\'a} and M{\'a}ria Tajt{\'a}kov{\'a} and Juraj Koska and {\vS}tefan Z{\'o}rad and V{\'i}ťazoslav Belan and Peter Vanuga and Juraj Payer and J{\"u}rgen Eckel and Iwar Klime{\vs} and Daniela Ga{\vs}per{\'i}kov{\'a}},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2008},
  volume={93 6},
  pages={2255-62}
}
CONTEXT GH deficiency (GHD) in adults is associated with central adiposity, dyslipidemia, and insulin resistance. OBJECTIVE The objective of the study was to test the hypothesis that GHD might change the spectrum of adipokines and thus influence the adipose tissue and the whole-body metabolic and inflammatory status leading to development of insulin resistance. DESIGN This was a single-center observational study with a cross-sectional design. PARTICIPANTS AND METHODS Protein arrays were… CONTINUE READING