Adipogenic potential of multiple human adenoviruses in vivo and in vitro in animals.

@article{Whigham2006AdipogenicPO,
  title={Adipogenic potential of multiple human adenoviruses in vivo and in vitro in animals.},
  author={Leah D. Whigham and Barbara A. Israel and Richard L. Atkinson},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2006},
  volume={290 1},
  pages={R190-4}
}
Human adenovirus-36 (Ad-36) increases adiposity in chickens, mice, and nonhuman primates and is associated with human obesity. Ad-36 paradoxically reduces serum cholesterol and triglycerides in animal models. Ad-36 increases adipocyte differentiation and triglyceride accumulation in 3T3-L1 cells in vitro. This study evaluated whether three other human adenoviruses increase adiposity in chickens and in 3T3-L1 cells in vitro. We inoculated chickens with human Ad-2, Ad-31, Ad-37, or media at age 3… CONTINUE READING