Adipogenic effect of calcium sensing receptor activation

@article{Villarroel2013AdipogenicEO,
  title={Adipogenic effect of calcium sensing receptor activation},
  author={P{\'i}a Villarroel and Marcela Reyes and Cecilia Fuentes and Mar{\'i}a Pia Segovia and Nicolas Vayas Tobar and Elisa Villalobos and Jorge Mart{\'i}nez and Eric R. Hugo and Nira Ben-Jonathan and Mariana Cifuentes},
  journal={Molecular and Cellular Biochemistry},
  year={2013},
  volume={384},
  pages={139-145}
}
We established that human adipose cells and the human adipose cell line LS14 express the calcium-sensing receptor (CaSR) and that its activation induces inflammatory cytokine production. Also, its expression is enhanced upon exposure to obesity-associated proinflammatory cytokines. We have thus proposed that CaSR activation may be associated with adipose dysfunction. Here, we evaluated a possible effect on adipogenesis. We induced adipose differentiation of primary and LS14 human preadipocytes… CONTINUE READING

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