Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size.

@article{Yin2014AdipocyteMF,
  title={Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size.},
  author={Xiao Lin Yin and Ian R Lanza and James M. Swain and Michael G Sarr and K. Sreekumaran Nair and Michael D Jensen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2014},
  volume={99 2},
  pages={
          E209-16
        }
}
CONTEXT It has been suggested that mitochondrial dysfunction in adipocytes contributes to obesity-related metabolic complications. However, obesity results in adipocyte hypertrophy, and large and small adipocytes from the same depot have different characteristics, raising the possibility that obesity-related mitochondrial defects are an inherent function of large adipocytes. OBJECTIVE Our goal was to examine whether obesity, independent of fat cell size and fat depot, is associated with… CONTINUE READING

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