Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.

@article{Floresta2017AdipocyteFA,
  title={Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.},
  author={Giuseppe Floresta and V. Pistar{\`a} and E. Amata and M. Dichiara and A. Marrazzo and O. Prezzavento and A. Rescifina},
  journal={European journal of medicinal chemistry},
  year={2017},
  volume={138},
  pages={
          854-873
        }
}
Small molecule inhibitors of adipocyte fatty acid binding protein 4 (FABP4) have attracted interest following the recent publications of beneficial pharmacological effects of these compounds. FABP4 is predominantly expressed in macrophages and adipose tissue where it regulates fatty acids (FAs) storage and lipolysis and is an important mediator of inflammation. In the past years, hundreds FABP4 inhibitors have been synthesized for effective atherosclerosis and diabetes treatments, including… Expand
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