Adhesion properties of human bladder cell lines with extracellular matrix components: the role of integrins and glycosylation.

@article{Lityska2002AdhesionPO,
  title={Adhesion properties of human bladder cell lines with extracellular matrix components: the role of integrins and glycosylation.},
  author={Anna Lityńska and Malgorzta Przybyło and Ewa Poche{\'c} and Piotr M. Laidler},
  journal={Acta biochimica Polonica},
  year={2002},
  volume={49 3},
  pages={643-50}
}
Integrin subunits present on human bladder cells displayed heterogeneous functional specificity in adhesion to extracellular matrix proteins (ECM). The non-malignant cell line (HCV29) showed significantly higher adhesion efficiency to collagen IV, laminin (LN) and fibronectin (FN) than cancer (T24, Hu456) and v-raf transfected (BC3726) cell lines. Specific antibodies to the alpha(2), alpha(5) and beta(1) integrin subunits inhibited adhesion of the non-malignant cells, indicating these integrin… CONTINUE READING

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