Adhesion patterns in early cell spreading.

@article{Ryzhkov2010AdhesionPI,
  title={Adhesion patterns in early cell spreading.},
  author={Pavel Ryzhkov and Marcus Prass and Meike Gummich and Jac-Simon K{\"u}hn and Christina Oettmeier and H. D{\"o}bereiner},
  journal={Journal of physics. Condensed matter : an Institute of Physics journal},
  year={2010},
  volume={22 19},
  pages={
          194106
        }
}
Mouse embryonic fibroblasts explore the chemical suitability before spreading on a given substrate. We find this early phase of cell spreading to be characterized by transient adhesion patches with a typical mean size of (1.0 ± 0.4) µm and a lifetime of (33 ± 12) s. Eventually, these patches fuse to initiate extensive spreading of the cell. We monitor cell adhesion using reflection interference contrast and total internal reflection fluorescence microscopy. Digital time lapse movies are… Expand

Topics from this paper

Initial cell adhesion of three cell types in the presence and absence of serum proteins
Contemporaneous cell spreading and phagocytosis: magneto-resistive real-time monitoring of membrane competing processes.
Cell-substrate interactions.
  • M. Gardel, U. Schwarz
  • Chemistry, Medicine
  • Journal of physics. Condensed matter : an Institute of Physics journal
  • 2010

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