Adhesion of tumour-infiltrating lymphocytes to endothelium: a phenotypic and functional analysis.


Efficacy of cancer immunotherapy with cultured tumour-infiltrating lymphocytes (TILs) depends upon infused TILs migrating into tumour-bearing tissue, in which they mediate an anti-tumour response. For TILs to enter a tumour, they must first bind to tumour endothelium, and this process depends on TILs expressing and regulating the function of relevant cell… (More)
DOI: 10.1038/bjc.1997.245


7 Figures and Tables