Adhesion of enteroaggregative Escherichia coli to pediatric intestinal mucosa in vitro.

@article{Hicks1996AdhesionOE,
  title={Adhesion of enteroaggregative Escherichia coli to pediatric intestinal mucosa in vitro.},
  author={Susan Hicks and David C. A Candy and Alan D. Phillips},
  journal={Infection and immunity},
  year={1996},
  volume={64 11},
  pages={4751-60}
}
Organ cultures of small- and large-intestinal mucosa from children were used to examine the interactions of enteroaggregative Escherichia coli (EAEC) with human intestine. Mucosae from patients aged between 3 and 190 months were cultured with five EAEC strains isolated from infants with diarrhea in the United Kingdom and with two well-described prototype EAEC strains, 17-2 and 221. The prototype strains adhered to jejunal, ileal, and colonic mucosae. The wild-type strains also adhered to this… CONTINUE READING

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Electron microscopy of infected small intestinal mucosa revealed bacteria in association with a thick mucus layer above an intact enterocyte brush border , which contained extruded cell fragments .
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