Adhesion of activated natural killer cells to tumor necrosis factor-alpha-treated endothelium under physiological flow conditions.

@article{Melder1996AdhesionOA,
  title={Adhesion of activated natural killer cells to tumor necrosis factor-alpha-treated endothelium under physiological flow conditions.},
  author={Robert J. Melder and Gerald C. Koenig and Lance L. Munn and Rakesh K. Jain},
  journal={Natural immunity},
  year={1996},
  volume={15 2-3},
  pages={154-63}
}
Adhesion of activated natural killer (A-NK) cells to activated and nonactivated endothelial cells in vitro was studied under dynamic flow conditions. Endothelial cells grown on glass slides were either treated with tumor necrosis factor-alpha (TNF alpha) or medium, then placed into a flow chamber over which suspensions of A-NK cells were passed using a range of defined shear stress levels. Significant numbers of binding cells could be consistently observed at shear stress levels less than 3 dyn… CONTINUE READING

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