Adhesion molecules. I: Keratinocyte-keratinocyte interactions; cadherins and pemphigus.

@article{Amagai1995AdhesionMI,
  title={Adhesion molecules. I: Keratinocyte-keratinocyte interactions; cadherins and pemphigus.},
  author={Masayuki Amagai},
  journal={The Journal of investigative dermatology},
  year={1995},
  volume={104 1},
  pages={146-52}
}
During the last few years, considerable progress has been made in our understanding of the structure and function of cadherins and of the pathophysiology of pemphigus. Cadherins are a multiple gene family of Ca(++)-dependent cell adhesion molecules with a typical single-spanning transmembrane structure. Cadherins have two major subfamilies, classic cadherin and desmosomal cadherin. Classic cadherins, including E-, P-, and N-cadherins, are characterized by a homophilic binding specificity. They… CONTINUE READING
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