Adhesion molecules in the stem cell niche--more than just staying in shape?

@article{Marthiens2010AdhesionMI,
  title={Adhesion molecules in the stem cell niche--more than just staying in shape?},
  author={V{\'e}ronique Marthiens and Ilias Kazanis and Lara Moss and Katherine Long and Charles ffrench-Constant},
  journal={Journal of cell science},
  year={2010},
  volume={123 Pt 10},
  pages={1613-22}
}
The expression of adhesion molecules by stem cells within their niches is well described, but what is their function? A conventional view is that these adhesion molecules simply retain stem cells in the niche and thereby maintain its architecture and shape. Here, we review recent literature showing that this is but one of their roles, and that they have essential functions in all aspects of the stem cell-niche interaction--retention, division and exit. We also highlight from this literature… CONTINUE READING

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