Adhesion molecules and transplantation.

  title={Adhesion molecules and transplantation.},
  author={Uwe W Heemann and Stefan G Tullius and Hiroyuki Azuma and J Kupiec-Weglinsky and Nicholas L. Tilney},
  journal={Annals of surgery},
  volume={219 1},
OBJECTIVE Accessory adhesion molecules are thought to influence the first interaction between host leukocytes and graft vascular endothelial cells. Their role in transplantation is reviewed. SUMMARY Adhesion molecules have been divided into three major families: the selectins, the integrins, and the immunoglobulin superfamily. Selectins are small proteins that mediate the first contact between stimulated endothelial cells and leukocytes. Integrins interact with cytoskeletal components of… CONTINUE READING
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