Adhesion molecules and their role in vascular disease.

  title={Adhesion molecules and their role in vascular disease.},
  author={C. F. Krieglstein and Daniel Neil Granger},
  journal={American journal of hypertension},
  volume={14 6 Pt 2},
A variety of recently discovered glycoproteins have been implicated in cell-cell interactions that are critical for normal hemostasis, immune surveillance, and vascular wall integrity. These cell adhesion molecules (CAM) are known to mediate blood cell (leukocyte, platelet)-endothelial cell interactions that can occur in all segments of the microvasculature under certain physiological (eg, hemostasis) and pathological (eg, inflammation) conditions. The multistep process of leukocyte recruitment… CONTINUE READING