Adhesion molecules: key players in Mesenchymal stem cell-mediated immunosuppression.

@article{Ren2011AdhesionMK,
  title={Adhesion molecules: key players in Mesenchymal stem cell-mediated immunosuppression.},
  author={Guangwen Ren and Arthur I. Roberts and Yufang Shi},
  journal={Cell adhesion & migration},
  year={2011},
  volume={5 1},
  pages={20-2}
}
Adhesion molecules are known to be important components of an active T cell-mediated immune response. Signals generated at a site of inflammation cause circulating T-cells to respond by rolling, arrest, and then transmigration through the endothelium, all of which are mediated by adhesion molecules. Consequently, strategies have been developed to treat immune disorders with specific antibodies that block the interaction of adhesion molecules. However, the therapeutic effects of such remedies… CONTINUE READING