Adhesion molecule polymorphisms in chronic renal allograft failure.

  title={Adhesion molecule polymorphisms in chronic renal allograft failure.},
  author={Andrew James McLaren and Sara E F Marshall and Neil A. Haldar and Charles G Mullighan and Susan V. Fuggle and Peter J. Morris and Ken Ian Welsh},
  journal={Kidney international},
  volume={55 5},
BACKGROUND Chronic allograft failure (CAF) is a major cause of late graft loss in renal transplantation. Up-regulation of adhesion molecules has been demonstrated in renal allograft biopsies during both acute and chronic rejection, and these molecules are known to regulate leukocyte migration into the graft. METHODS A single-center retrospective study was… CONTINUE READING