Adhesion Protein Protocols

Abstract

Integrin activation leads to an increased affi nity for the extracellular matrix and regulates many cellular processes such as cell adhesion and migration. To capture the process of integrin inside-out activation in a purifi ed system, we describe here methods to isolate platelet αIIbβ3 integrins in the inactive state and to incorporate them into… (More)
DOI: 10.1007/978-1-62703-538-5

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