Adhesion Molecules of Cultured Hematopoietic Malignancies

  • Hazel Ebling
  • Published 2013
This study documents that a calcium-dependent phosphomannosyl-binding site on human lymphoid malignancies mediates attachment to the peripheral node high endothelial venule (PNHEV). The phorbol ester PMAcoordinately upregulates lectin activity and binding to the PNHEVin the human T-lymphoblastic cell line Jurkat but not in the less phenotypically mature… CONTINUE READING