Adhesion G Protein-coupled Receptors

  title={Adhesion G Protein-coupled Receptors},
  author={Tobias Langenhan},
  booktitle={Handbook of Experimental Pharmacology},
Since the discovery of adhesion G-protein-coupled receptors (aGPCRs) 20 years ago, reverse genetics approaches have dominated the elucidation of their function and work mechanisms. Seminal findings in this field comprise the description of aGPCRs as seven-transmembrane (7TM) molecules with an extended extracellular region, the identification of… CONTINUE READING