Adherent-invasive Escherichia coli and Crohn's disease

@article{Barnich2007AdherentinvasiveEC,
  title={Adherent-invasive Escherichia coli and Crohn's disease},
  author={N. Barnich and A. Darfeuille‐Michaud},
  journal={Current Opinion in Gastroenterology},
  year={2007},
  volume={23},
  pages={16–20}
}
Purpose of review The identification of mutations in the nucleotide oligomerization domain 2-encoding gene in patients with Crohn's disease suggests a link between the innate immune response to invasive bacteria and the development of Crohn's disease. Herein, we review reports concerning the association of pathogenic Escherichia coli with the intestinal mucosa of Crohn's disease patients. Recent findings Adherent-invasive E. coli were isolated from ileal biopsies of 36.4% of patients with ileal… Expand
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