Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease.

@article{DarfeuilleMichaud2002AdherentinvasiveEC,
  title={Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease.},
  author={Arlette Darfeuille-Michaud},
  journal={International journal of medical microbiology : IJMM},
  year={2002},
  volume={292 3-4},
  pages={185-93}
}
Crohn's disease (CD) is an inflammatory bowel disease (IBD) of unknown aetiology. Genetically engineered rodent models showed that IBDs are immunologically mediated and that luminal bacteria play an essential role in the development of the inflammation. Various bacterial pathogens have been incriminated but results have been conflicting. A new pathovar of E. coli, designated adherent-invasive Escherichia coli (AIEC) may be associated with CD. AIEC strains colonize the intestinal mucosa by… CONTINUE READING