Adherence to gastroprotection and the risk of NSAID-related upper gastrointestinal ulcers and haemorrhage.

@article{Soest2007AdherenceTG,
  title={Adherence to gastroprotection and the risk of NSAID-related upper gastrointestinal ulcers and haemorrhage.},
  author={Eva Marianne van Soest and Miriam C. J. M. Sturkenboom and Jeanne P. Dieleman and Katia M C Verhamme and Peter D. Siersema and Ernst J Kuipers},
  journal={Alimentary pharmacology & therapeutics},
  year={2007},
  volume={26 2},
  pages={265-75}
}
BACKGROUND Upper gastrointestinal (UGI) complications are a well-recognized risk of NSAID treatment, requiring preventive measures in high-risk patients. Adherence to gastroprotective agents (GPAs) in NSAID users has been suggested to be suboptimal. AIM To investigate the association between adherence to GPAs (proton pump inhibitors or H(2)-receptor antagonists) and the risk of NSAID-related UGI ulcers or haemorrhage in high-risk patients. METHODS A population-based nested case-control… CONTINUE READING
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