Adherence-resistance relationships to combination HIV antiretroviral therapy

@article{Bangsberg2007AdherenceresistanceRT,
  title={Adherence-resistance relationships to combination HIV antiretroviral therapy},
  author={David R. Bangsberg and Deanna L Kroetz and Steven G. Deeks},
  journal={Current HIV/AIDS Reports},
  year={2007},
  volume={4},
  pages={65-72}
}
Early views on the relationship between adherence and resistance postulated a bell-shaped relationship that balanced selective drug pressure and improved viral suppression along a continuum of adherence. Although this conceptual relationship remains valid, recent data suggest that each regimen class may have different adherence-resistance relationships. These regimen-specific relationships are a function of the capacities of resistant virus to replicate at different levels of drug exposure… 
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