Adherence of Pasteurella multocida to fibronectin.

  title={Adherence of Pasteurella multocida to fibronectin.},
  author={S Mady Dabo and Anthony W. Confer and Steven D. Hartson},
  journal={Veterinary microbiology},
  volume={110 3-4},
For many pathogens, adherence and/or invasion involve association with host extracellular matrix molecules, such as fibronectin (Fn). Pasteurella multocida was found to bind significantly to Fn and collagen type IX but not to laminin and collagen types IV and X. The binding of P. multocida to Fn was dose-dependent and was inhibited by heparin (Hep). Removal of polysaccharide capsule enhanced the binding capacity of the bacterium to Fn and inhibition by Hep. Protease treatment of bacteria… CONTINUE READING


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